Li Wengang

Li Wengang

Title: Professor, Ph.D Supervisor

Degree: M.D, Ph.D

Department: Department of Clinical Medicine

Research field: Hepatobiliary and pancreatic surgery


 

Research Focus

Basic and applied research on the pathogenesis and precision diagnosis and treatment of abdominal tumors, especially retroperitoneal tumors


Educational background:

1. 1988~1993: Bethune Medical University, Bachelor of Medicine;

2. 1998~2000: Bethune Medical University, Sino-Japanese Union Hospital, Department of General Surgery; Master of Medicine

3. 2001~2002: Oriental Hepatobiliary Surgery Hospital, Shanghai Second Military Medical University; Study;

4. 2002~2005: Chinese Department of Hepatobiliary Surgery, PLA General Hospital; MD;

 5. 2012~2013: Jackson Memorial Hospital, University of Miami, USA; Study visits


Work experience:

1. 2005.8-2007.1: Attending physician of the First Affiliated Hospital of Xiamen University

2. 2007.2 to 2008.7: he was a postdoctoral fellow at the Liver Transplant Center of Shanghai First People's Hospital affiliated to Shanghai Jiaotong University

3. 2008.8-2011.2: Deputy Chief Physician, First Affiliated Hospital of Xiamen University

4. 2011.3-2018.5: Chief Physician, Chenggong Hospital Affiliated to Xiamen University

5. 2018.6-present: Chief physician of Xiang'an Hospital Affiliated to Xiamen University (directly subordinate).

6. 2018.6-present: Deputy Dean of School of Medicine, Xiamen University

7. 2018.6-present: Deputy Director of Anti-Cancer Research Center, Xiamen University

 

Selected Publications

1. Peng Kesong, Kou Lele, Yu Li, Bai Chaonan, Li Ming, Mo Pingli, Li Wengang, Yu Chundong.Histone Demethylase JMJD2D Interacts with Beta-catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice. [J] Gastroenterology, 2019, 156: 1112-1126.(通讯作者)IF: 22.682

2. Qiang Chen,Wenjiao Li,Yunyan Wan,Xiaochun Xia,Qiao Wu,Yanling Chen,Zhide Lai,Chundong Yu and Wengang Li.Amplified in Breast Cancer 1 Enhances HumanCholangiocarcinoma Growth and Chemoresistance by Simultaneous Activation of Akt and Nrf2 Pathways. [J]Hepatology, 2012,55(6):1820-1829. (通讯作者)IF:14.67

3. Yonghong Liu, Zhangwei Tong,1 Ting Li, Qiang Chen, Luting Zhuo, WengangLi,Ray-Chang Wu and Chundong Yu .Hepatitis B Virus X Protein Stabilizes Amplified inBreast Cancer 1 Protein and Cooperates WithIt to Promote Human Hepatocellular Carcinoma Cell Invasiveness . [J] Hepatology,2012,56(3):1015-1024.IF:14.67

4. Yixiang Xu, Qiang Chen, Wen-Gang Li, Xinhui Su, Tenghui Chen, Yang Zhao and Chundong Yu.Overexpression of transcriptional coactivator AIB1 promotes hepatocellular carcinoma progression by enhancing cell proliferation and invasiveness. [J]Oncogene, 2010 Jun 10;29(23):3386-97.IF:7.97

5. Zhang Xiaojie, Zhou Changsheng, Wu Fanghua, Gao Chang, Liu Qianqian, Lv Peng, Li Ming, Huang Liyong, Wu Ting, Li Wengang. Bio-engineered nano-vesicles for IR820 delivery: a therapy platform for cancer by surgery and photothermal therapy. [J]. Nanoscale, 2022, 14: 2780-2792. (通讯作者) IF7.790

6. Chen Qiang, Zhuang Shuqing, Hong Yilin, Yang Lingtao, Guo Peng, Mo Pingli, Peng Kesong., Li Wengang, Xiao Nengming, Yu Chundong. Demethylase JMJD2D induces PD-L1 expression to promote colorectal cancer immune escape by enhancing IFNGR1-STAT3-IRF1 signaling. [J]. Oncogene, 2022, undefined: undefined.(通讯作者) IF9.867

7. Xia RM, Liu T, Li WG, Xu XQ. RNAbinding protein RBM24 represses colorectal tumourigenesis by stabilising PTEN mRNA [J]. Clin Transl Med. 2021 Oct 12;11(10):e383..(通讯作者)IF: 11.492

8. Xie Fu'an, Qin Dongmei, Lian Lanlan, Li Ming, Kong Xu, Xia Xiaogang, Yu Chundong, Luo Chenghua, Li Wengang. Establishment of an orthotopic perirenal space xenograft mouse model of retroperitoneal sarcoma.[J] .Cancer Commun (Lond), 2021, 41: 631-634. (通讯作者)IF: 10.392

9. Li Ming, Deng Yuan, Zhuo Minghui, Zhou Hui, Kong Xu, Xia Xiaogang, Su Zhaojie, Chen Qiang, Guo Peng, Mo Pingli, Yu Chundong, Li Wengang. Demethylase-independent function of JMJD2D as a novel antagonist of p53 to promote Liver Cancer initiation and progression.[J].Theranostics, 2020, 10: 8863-8879. (通讯作者)IF: 11.556

10. Zhuo Minghui, Chen Wenbo, Shang Shaohui, Guo Peng, Peng Kesong, Li Ming, Mo Pingli, Zhang Yongyou, Qiu Xingfeng, Li Wengang, Yu Chundong. Inflammation-induced JMJD2D promotes colitis recovery and colon tumorigenesis by activating Hedgehog signaling[J]Oncogene, 202039: 3336-3353(通讯作者)IF: 9.867

11. Ting-Dong Yan, Hua Wu, Hai-Ping Zhang, Na Lu, Ping Ye, Feng-Hai Yu, Hu Zhou, Wen-Gang Li,et al.Oncogenic Potential of Retinoic Acid Receptor-γin Hepatocellular Carcinoma. [J]Cancer Research, 2010 Mar 15;70(6):2285-95.IF:9.72