Research focus:The main research area is ion channels and diseases, including the role of ion channels in ischemic stroke and the electrophysiological mechanisms of the occurrence and development of myocarditis.
Education Background:
Sep.1982 --- Jul.1986 Bachelor's degree, Department of Applied Physics, Sichuan University.
Sep.1986 --- Jul.1989 Master degree, Department of Applied Physics, Beijing University of Technology.
April.1994 ---March.1998 Doctor degree, Department of Physiology, Nagoya University School of Medicine.
Work experience:
September 1989- July 1993: Teaching Assistant and Lecturer, Department of Biomedical Engineering, Capital Medical University
April 1998- March 2001: Research Association, Department of Cell Biophysics, Department of Medicine, Nagoya University, Japan
April 2001- June 2003: Researcher at the Japan Science and Technology Revitalization Corps (JST) [Cell Force Sensing Project]
June 2003- June 2009: Institute of Biophysics, Chinese Academy of Sciences/Research Team Leader, State Key Laboratory of Brain and Cognition, Doctoral Supervisor
June 2009 --Now: professor and doctoral supervisor of Basic School of Medicine, Xiamen University
Selected Publications:
1、Chi S., Cai W., Liu P., Zhang Z., Chen X., Gao L., Qi J., Bi L., Chen L*., Qi Z*. Baifuzi reduces transient ischemic brain damage via interaction with STREX domain of BKCa channels. Cell Death & Disease 1, e13 (2010).
2、Fan Z, Bi LJ*, Jin G*, Qi Z*. Electrostatic interaction in the NH(2)-terminus accelerates inactivation of the Kv1.4 channel. Biochim Biophys Acta. 1798:2076-2083, (2010)
3、Wang Y, Shi X *, Qi Z *. Hypericin prolongs action potential duration by acting on neuronal K+ channels. Br J Pharmacol. 159:1402-1407, (2010).
4、He F, Liu W, Zheng S, Zhou L, Ye B* and Qi Z*. Ion transport through dimethyl sulfoxide (DMSO) induced transient water pores in cell membranes. Mol Membr Biol. 29:107-113, (2012)
5、Fan Z, Zhang Z, Fu M, Qi Z*, Xiao Z*. Effect of inserting charged peptide at NH(2)-terminal on N-type inactivation of Kv1.4 channel. Biochim Biophys Acta. 1828:990-996, (2013).
6、Zhou L.#, Zhang Y#., Gao L., Ye Y., Qi J*., Qi Z*. Structure-activity relationship of Baifuzi-cerebrosides on BKCa channel activation. Eur J Med Chem. 75:301-307, (2014).
7、Zhang Y., Zhou L., Zou J., Wang M., Qi J., Qi Z*. Palmitoylation of STREX domain confers cerebroside sensitivity to the BKCa channel. BBA- Biomembranes. 1838: 2451–2459 (2014).
8、Hua-Juan Li, Yu-Jiao Zhang, Li Zhou, Feng Han, Ming-Yan Wang, Mao-Qiang Xue*, Zhi Qi*. Chlorpromazine confers neuroprotection against brain ischemia by activating BKCa channel. Euro J Pharmacol. 735:38-43 (2014).
9、Jun Zou*, Xiao-Yang Yue, Sheng-Chao Zheng, Guanwei Zhang, He Chang, Yan-Chun Liao, Ye Zhang, Mao-Qiang Xue, Zhi Qi* Cholesterol modulates function of connexin 43 gap junction channel via PKC pathway in H9c2 cells. BBA– Biomembranes. 1838:2019-2025, (2014).
10、Wu P, Gao Z, Ye S, Qi Z*. Nitric oxide inhibits the basolateral 10-pS Cl- channels through cGMP/PKG signaling pathway in the thick ascending limb of C57BL/6 mice. Am J Physiol Renal Physiol 310: F755–F762, (2016)
